| Season | Team | League | GP | G | A | TP | PIM |
| 2004-2005 | Cushing Academy | USHS-Prep | 34 | 0 | 1 | 1 | - |
| 2005-2006 | Cushing Academy | USHS-Prep | 36 | 1 | 16 | 17 | - |
| 2006-2007 | Peterborough Petes | OHL | 67 | 7 | 26 | 33 | 63 |
| 2007-2008 | Peterborough Petes | OHL | 60 | 11 | 50 | 61 | 72 |
| 2008-2009 | Atlanta Thrashers | NHL | 47 | 9 | 10 | 19 | 47 |
| Chicago Wolves | AHL | 5 | 1 | 0 | 1 | 0 | |
| USA | WC | 9 | 0 | 1 | 1 | 2 | |
| 2009-2010 | Atlanta Thrashers | NHL | 81 | 10 | 13 | 23 | 61 |
| 2010-2011 | Atlanta Thrashers | NHL | 71 | 5 | 12 | 17 | 29 |
| 2011-2012 | Winnipeg Jets | NHL | 65 | 5 | 25 | 30 | 71 |
| 2012-2013 | Winnipeg Jets | NHL | 33 | 5 | 9 | 14 | 29 |
| 2013-2014 | Winnipeg Jets | NHL | 55 | 3 | 8 | 11 | 48 |
| 2014-2015 | Winnipeg Jets | NHL | 41 | 3 | 10 | 13 | 40 |
| Buffalo Sabres | NHL | 21 | 0 | 7 | 7 | 38 | |
| 2015-2016 | Buffalo Sabres | NHL | 64 | 7 | 17 | 24 | 68 |
| 2016-2017 | Buffalo Sabres | NHL | 56 | 2 | 9 | 11 | 46 |
| 2017-2018 | Buffalo Sabres | NHL | 18 | 0 | 1 | 1 | 20 |
| 2018-2019 | Buffalo Sabres | NHL | 65 | 3 | 16 | 19 | 52 |
| 2019-2020 | Buffalo Sabres | NHL | 19 | 1 | 4 | 5 | 10 |
| Tampa Bay Lightning | NHL | 8 | 0 | 2 | 2 | 12 | |
| 2020-2021 | Toronto Maple Leafs | NHL | 45 | 0 | 4 | 4 | 49 |
| 2021-2022 | Tampa Bay Lightning | NHL | 48 | 3 | 5 | 8 | 53 |
| 2022-2023 | Tampa Bay Lightning | NHL | 46 | 1 | 4 | 5 | 42 |
| 2023-2024 | Tampa Bay Lightning | NHL | 4 | 0 | 0 | 0 | 0 |
| Minnesota Wild | NHL | 61 | 3 | 11 | 14 | 63 | |
| 2024-2025 | Minnesota Wild | NHL | 81 | 4 | 12 | 16 | 43 |