| 1. | Henrik Sedin (C) | Vancouver Canucks | 82 | 29 | 83 | 112 | 1.37 | 48 | 35 |
| 2. | Sidney Crosby (C) | Pittsburgh Penguins | 81 | 51 | 58 | 109 | 1.35 | 71 | 15 |
| 3. | Alexander Ovechkin (LW/RW) | Washington Capitals | 72 | 50 | 59 | 109 | 1.51 | 89 | 45 |
| 4. | Nicklas Bäckström (C) | Washington Capitals | 82 | 33 | 68 | 101 | 1.23 | 50 | 37 |
| 5. | Steven Stamkos (C/W) | Tampa Bay Lightning | 82 | 51 | 44 | 95 | 1.16 | 38 | -2 |
| 6. | Martin St-Louis (RW) | Tampa Bay Lightning | 82 | 29 | 65 | 94 | 1.15 | 12 | -8 |
| 7. | Brad Richards (C) | Dallas Stars | 80 | 24 | 67 | 91 | 1.14 | 14 | -12 |
| 8. | Joe Thornton (C) | San Jose Sharks | 79 | 20 | 69 | 89 | 1.13 | 54 | 17 |
| 9. | Patrick Kane (RW/LW) | Chicago Blackhawks | 82 | 30 | 58 | 88 | 1.07 | 20 | 16 |
| 10. | Marián Gáborík (RW) | New York Rangers | 76 | 42 | 44 | 86 | 1.13 | 37 | 15 |
| 11. | Ilya Kovalchuk (LW) | totals | 76 | 41 | 44 | 85 | 1.12 | 53 | 10 |
| Atlanta Thrashers | Atlanta Thrashers | 49 | 31 | 27 | 58 | 1.18 | 45 | 1 |
| New Jersey Devils | New Jersey Devils | 27 | 10 | 17 | 27 | 1.00 | 8 | 9 |
| 12. | Daniel Sedin (LW) | Vancouver Canucks | 63 | 29 | 56 | 85 | 1.35 | 28 | 36 |
| 13. | Alexander Syomin (LW) | Washington Capitals | 73 | 40 | 44 | 84 | 1.15 | 66 | 36 |
| 14. | Patrick Marleau (LW) | San Jose Sharks | 82 | 44 | 39 | 83 | 1.01 | 22 | 21 |
| 15. | Dany Heatley (LW) | San Jose Sharks | 82 | 39 | 43 | 82 | 1.00 | 54 | 14 |
| 16. | Zach Parise (LW/RW) | New Jersey Devils | 81 | 38 | 44 | 82 | 1.01 | 32 | 24 |
| 17. | Anze Kopitar (C/LW) | Los Angeles Kings | 82 | 34 | 47 | 81 | 0.99 | 16 | 6 |
| 18. | Paul Stastny (C) | Colorado Avalanche | 81 | 20 | 59 | 79 | 0.98 | 50 | 2 |
| 19. | Yevgeni Malkin (C) | Pittsburgh Penguins | 67 | 28 | 49 | 77 | 1.15 | 100 | -6 |
| 20. | Corey Perry (RW/LW) | Anaheim Ducks | 82 | 27 | 49 | 76 | 0.93 | 111 | 0 |
| 21. | Mike Green (D) | Washington Capitals | 75 | 19 | 57 | 76 | 1.01 | 54 | 39 |
| 22. | Ryan Kesler (C) | Vancouver Canucks | 82 | 25 | 50 | 75 | 0.91 | 104 | 1 |
| 23. | Loui Eriksson (LW) | Dallas Stars | 82 | 29 | 42 | 71 | 0.87 | 26 | -4 |
| 24. | Mikko Koivu (C) | Minnesota Wild | 80 | 22 | 49 | 71 | 0.89 | 50 | -2 |
| 25. | Daniel Alfredsson (RW) | Ottawa Senators | 70 | 20 | 51 | 71 | 1.01 | 22 | 8 |
| 26. | Eric Staal (C) | Carolina Hurricanes | 70 | 29 | 41 | 70 | 1.00 | 68 | 4 |
| 27. | Pavel Datsyuk (C) | Detroit Red Wings | 80 | 27 | 43 | 70 | 0.88 | 18 | 17 |
| 28. | Tomas Plekanec (C) | Montréal Canadiens | 82 | 25 | 45 | 70 | 0.85 | 50 | 5 |
| 29. | Vincent Lecavalier (C) | Tampa Bay Lightning | 82 | 24 | 46 | 70 | 0.85 | 63 | -16 |
| 30. | Henrik Zetterberg (C) | Detroit Red Wings | 74 | 23 | 47 | 70 | 0.95 | 26 | 12 |
| 31. | Jarome Iginla (RW) | Calgary Flames | 82 | 32 | 37 | 69 | 0.84 | 58 | -2 |
| 32. | Derek Roy (C) | Buffalo Sabres | 80 | 26 | 43 | 69 | 0.86 | 48 | 9 |
| 33. | Ryan Getzlaf (C) | Anaheim Ducks | 66 | 19 | 50 | 69 | 1.05 | 79 | 4 |
| 34. | Duncan Keith (D) | Chicago Blackhawks | 82 | 14 | 55 | 69 | 0.84 | 51 | 21 |
| 35. | Jonathan Toews (C) | Chicago Blackhawks | 76 | 25 | 43 | 68 | 0.89 | 47 | 22 |
| 36. | Alexandre Burrows (RW/LW) | Vancouver Canucks | 82 | 35 | 32 | 67 | 0.82 | 121 | 34 |
| 37. | Rick Nash (LW) | Columbus Blue Jackets | 76 | 33 | 34 | 67 | 0.88 | 58 | -2 |
| 38. | Travis Zajac (C/RW) | New Jersey Devils | 82 | 25 | 42 | 67 | 0.82 | 24 | 22 |
| 39. | Nikolai Antropov (C/W) | Atlanta Thrashers | 76 | 24 | 43 | 67 | 0.88 | 44 | 13 |
| 40. | Patrick Sharp (LW/RW) | Chicago Blackhawks | 82 | 25 | 41 | 66 | 0.80 | 28 | 24 |
| 41. | Jussi Jokinen (W/C) | Carolina Hurricanes | 81 | 30 | 35 | 65 | 0.80 | 36 | 3 |
| 42. | Antoine Vermette (C) | Columbus Blue Jackets | 82 | 27 | 38 | 65 | 0.79 | 32 | 2 |
| 43. | Wojtek Wolski (LW/RW) | totals | 80 | 23 | 42 | 65 | 0.81 | 27 | 21 |
| Colorado Avalanche | Colorado Avalanche | 62 | 17 | 30 | 47 | 0.76 | 21 | 15 |
| Arizona Coyotes | Arizona Coyotes | 18 | 6 | 12 | 18 | 1.00 | 6 | 6 |
| 44. | Tim Connolly (C) | Buffalo Sabres | 73 | 17 | 48 | 65 | 0.89 | 28 | 10 |
| 45. | Bobby Ryan (RW/LW) | Anaheim Ducks | 81 | 35 | 29 | 64 | 0.79 | 81 | 9 |
| 46. | Chris Stewart (RW/LW) | Colorado Avalanche | 77 | 28 | 36 | 64 | 0.83 | 73 | 4 |
| 47. | Dustin Penner (LW) | Edmonton Oilers | 82 | 32 | 31 | 63 | 0.77 | 38 | 6 |
| 48. | Kristian Huselius (LW) | Columbus Blue Jackets | 74 | 23 | 40 | 63 | 0.85 | 36 | -4 |
| 49. | Mike Richards (C) | Philadelphia Flyers | 82 | 31 | 31 | 62 | 0.76 | 79 | -2 |
| 50. | Jason Pominville (RW) | Buffalo Sabres | 82 | 24 | 38 | 62 | 0.76 | 22 | 13 |
| 51. | Jeff Carter (C) | Philadelphia Flyers | 74 | 33 | 28 | 61 | 0.82 | 38 | 2 |
| 52. | Andrew Brunette (LW) | Minnesota Wild | 82 | 25 | 36 | 61 | 0.74 | 12 | -5 |
| 53. | Maxim Afinogenov (RW/LW) | Atlanta Thrashers | 82 | 24 | 37 | 61 | 0.74 | 46 | -17 |
| 54. | Jamie Langenbrunner (RW) | New Jersey Devils | 81 | 19 | 42 | 61 | 0.75 | 44 | 6 |
| 55. | Stephen Weiss (C) | Florida Panthers | 80 | 28 | 32 | 60 | 0.75 | 40 | -7 |
| 56. | Brooks Laich (C/LW) | Washington Capitals | 78 | 25 | 34 | 59 | 0.76 | 34 | 16 |
| 57. | Drew Doughty (D) | Los Angeles Kings | 82 | 16 | 43 | 59 | 0.72 | 54 | 20 |
| 58. | Scott Gomez (C) | Montréal Canadiens | 78 | 12 | 47 | 59 | 0.76 | 60 | 1 |
| 59. | René Bourque (LW/RW) | Calgary Flames | 73 | 27 | 31 | 58 | 0.79 | 88 | 7 |
| 60. | Ray Whitney (LW/RW) | Carolina Hurricanes | 80 | 21 | 37 | 58 | 0.73 | 26 | -6 |
| 61. | Václav Prospal (LW/C) | New York Rangers | 75 | 20 | 38 | 58 | 0.77 | 32 | 8 |
| 62. | Dan Boyle (D) | San Jose Sharks | 76 | 15 | 43 | 58 | 0.76 | 70 | 6 |
| 63. | Andy McDonald (C) | St. Louis Blues | 79 | 24 | 33 | 57 | 0.72 | 18 | -9 |
| 64. | Jason Spezza (C) | Ottawa Senators | 60 | 23 | 34 | 57 | 0.95 | 20 | 0 |
| 65. | Nathan Horton (RW) | Florida Panthers | 65 | 20 | 37 | 57 | 0.88 | 42 | -1 |
| 66. | Matt Stajan (C) | totals | 82 | 19 | 38 | 57 | 0.70 | 32 | -6 |
| Toronto Maple Leafs | Toronto Maple Leafs | 55 | 16 | 25 | 41 | 0.75 | 30 | -3 |
| Calgary Flames | Calgary Flames | 27 | 3 | 13 | 16 | 0.59 | 2 | -3 |
| 67. | Ryane Clowe (LW) | San Jose Sharks | 82 | 19 | 38 | 57 | 0.70 | 131 | 0 |
| 68. | Dustin Brown (RW/LW) | Los Angeles Kings | 82 | 24 | 32 | 56 | 0.68 | 41 | -6 |
| 69. | Phil Kessel (RW) | Toronto Maple Leafs | 70 | 30 | 25 | 55 | 0.79 | 21 | -8 |
| 70. | James Neal (LW/RW) | Dallas Stars | 78 | 27 | 28 | 55 | 0.71 | 64 | -5 |
| 71. | Matt Duchene (C/W) | Colorado Avalanche | 81 | 24 | 31 | 55 | 0.68 | 16 | 1 |
| 72. | R.J. Umberger (C/W) | Columbus Blue Jackets | 82 | 23 | 32 | 55 | 0.67 | 40 | -16 |
| 73. | Rich Peverley (C) | Atlanta Thrashers | 82 | 22 | 33 | 55 | 0.67 | 36 | -14 |
| 74. | Shane Doan (RW) | Arizona Coyotes | 82 | 18 | 37 | 55 | 0.67 | 41 | 3 |
| 75. | Chris Pronger (D) | Philadelphia Flyers | 82 | 10 | 45 | 55 | 0.67 | 79 | 22 |
| 76. | John Tavares (C/LW) | New York Islanders | 82 | 24 | 30 | 54 | 0.66 | 22 | -15 |
| 77. | Martin Havlát (RW/LW) | Minnesota Wild | 73 | 18 | 36 | 54 | 0.74 | 34 | -19 |
| 78. | Mikael Samuelsson (RW) | Vancouver Canucks | 74 | 30 | 23 | 53 | 0.72 | 64 | 10 |
| 79. | Mike Knuble (RW) | Washington Capitals | 69 | 29 | 24 | 53 | 0.77 | 59 | 23 |
| 80. | Thomas Vanek (LW/RW) | Buffalo Sabres | 71 | 28 | 25 | 53 | 0.75 | 42 | 9 |
| 81. | Daniel Brière (C) | Philadelphia Flyers | 75 | 26 | 27 | 53 | 0.71 | 71 | -2 |
| 82. | Mike Fisher (C) | Ottawa Senators | 79 | 25 | 28 | 53 | 0.67 | 59 | 1 |
| 83. | Mason Raymond (LW/RW) | Vancouver Canucks | 82 | 25 | 28 | 53 | 0.65 | 48 | 0 |
| 84. | Ryan Smyth (LW) | Los Angeles Kings | 67 | 22 | 31 | 53 | 0.79 | 42 | 8 |
| 85. | Mike Ribeiro (C) | Dallas Stars | 66 | 19 | 34 | 53 | 0.80 | 38 | -5 |
| 86. | Matthew Lombardi (C) | Arizona Coyotes | 78 | 19 | 34 | 53 | 0.68 | 36 | 8 |
| 87. | Saku Koivu (C) | Anaheim Ducks | 71 | 19 | 33 | 52 | 0.73 | 36 | 14 |
| 88. | Patrice Bergeron (C) | Boston Bruins | 73 | 19 | 33 | 52 | 0.71 | 28 | 6 |
| 89. | Kyle Okposo (RW/C) | New York Islanders | 80 | 19 | 33 | 52 | 0.65 | 34 | -22 |
| 90. | David Krejčí (C) | Boston Bruins | 79 | 17 | 35 | 52 | 0.66 | 26 | 8 |
| 91. | Patric Hörnqvist (RW) | Nashville Predators | 80 | 30 | 21 | 51 | 0.64 | 40 | 18 |
| 92. | Joe Pavelski (C/RW) | San Jose Sharks | 67 | 25 | 26 | 51 | 0.76 | 26 | 1 |
| 93. | Marián Hossa (RW) | Chicago Blackhawks | 57 | 24 | 27 | 51 | 0.89 | 18 | 24 |
| 94. | Tomas Fleischmann (LW) | Washington Capitals | 69 | 23 | 28 | 51 | 0.74 | 28 | 9 |
| 95. | Alexander Frolov (LW) | Los Angeles Kings | 81 | 19 | 32 | 51 | 0.63 | 26 | -1 |
| 96. | Steve Sullivan (LW) | Nashville Predators | 82 | 17 | 34 | 51 | 0.62 | 35 | 2 |
| 97. | Michael Cammalleri (LW) | Montréal Canadiens | 65 | 26 | 24 | 50 | 0.77 | 16 | 7 |
| 98. | Alexei Ponikarovsky (LW) | totals | 77 | 21 | 29 | 50 | 0.65 | 61 | -1 |
| Toronto Maple Leafs | Toronto Maple Leafs | 61 | 19 | 22 | 41 | 0.67 | 44 | 5 |
| Pittsburgh Penguins | Pittsburgh Penguins | 16 | 2 | 7 | 9 | 0.56 | 17 | -6 |
| 99. | Jakub Voráček (RW) | Columbus Blue Jackets | 81 | 16 | 34 | 50 | 0.62 | 26 | -7 |
| 100. | Olli Jokinen (C) | totals | 82 | 15 | 35 | 50 | 0.61 | 75 | 3 |
| Calgary Flames | Calgary Flames | 56 | 11 | 24 | 35 | 0.63 | 53 | 2 |
| New York Rangers | New York Rangers | 26 | 4 | 11 | 15 | 0.58 | 22 | 1 |