| 1. | Connor McDavid (C) | Edmonton Oilers | 56 | 33 | 72 | 105 | 1.88 | 20 | 21 |
| 2. | Leon Draisaitl (C/W) | Edmonton Oilers | 56 | 31 | 53 | 84 | 1.50 | 22 | 29 |
| 3. | Brad Marchand (LW) | Boston Bruins | 53 | 29 | 40 | 69 | 1.30 | 46 | 26 |
| 4. | Mitchell Marner (RW/C) | Toronto Maple Leafs | 55 | 20 | 47 | 67 | 1.22 | 20 | 21 |
| 5. | Auston Matthews (C/LW) | Toronto Maple Leafs | 52 | 41 | 25 | 66 | 1.27 | 10 | 21 |
| 6. | Mikko Rantanen (W/C) | Colorado Avalanche | 52 | 30 | 36 | 66 | 1.27 | 34 | 30 |
| 7. | Patrick Kane (RW/LW) | Chicago Blackhawks | 56 | 15 | 51 | 66 | 1.18 | 14 | -7 |
| 8. | Nathan MacKinnon (C/RW) | Colorado Avalanche | 48 | 20 | 45 | 65 | 1.35 | 37 | 22 |
| 9. | Mark Scheifele (C) | Winnipeg Jets | 56 | 21 | 42 | 63 | 1.13 | 12 | -4 |
| 10. | Sidney Crosby (C) | Pittsburgh Penguins | 55 | 24 | 38 | 62 | 1.13 | 26 | 8 |
| 11. | Mark Stone (RW) | Vegas Golden Knights | 55 | 21 | 40 | 61 | 1.11 | 28 | 26 |
| 12. | Jonathan Huberdeau (LW/RW) | Florida Panthers | 55 | 20 | 41 | 61 | 1.11 | 36 | 12 |
| 13. | Aleksander Barkov (C/LW) | Florida Panthers | 50 | 26 | 32 | 58 | 1.16 | 14 | 12 |
| 14. | David Perron (LW/RW) | St. Louis Blues | 56 | 19 | 39 | 58 | 1.04 | 22 | 6 |
| 15. | Artemi Panarin (LW) | New York Rangers | 42 | 17 | 41 | 58 | 1.38 | 6 | 14 |
| 16. | Sebastian Aho (C/W) | Carolina Hurricanes | 56 | 24 | 33 | 57 | 1.02 | 32 | 16 |
| 17. | Jake Guentzel (LW) | Pittsburgh Penguins | 56 | 23 | 34 | 57 | 1.02 | 28 | 7 |
| 18. | Alex DeBrincat (RW/LW) | Chicago Blackhawks | 52 | 32 | 24 | 56 | 1.08 | 12 | 3 |
| 19. | Ryan O'Reilly (C) | St. Louis Blues | 56 | 24 | 30 | 54 | 0.96 | 18 | 26 |
| 20. | Nicklas Bäckström (C) | Washington Capitals | 55 | 15 | 38 | 53 | 0.96 | 14 | 0 |
| 21. | Gabriel Landeskog (LW/RW) | Colorado Avalanche | 54 | 20 | 32 | 52 | 0.96 | 34 | 14 |
| 22. | Kirill Kaprizov (LW) | Minnesota Wild | 55 | 27 | 24 | 51 | 0.93 | 16 | 10 |
| 23. | Joe Pavelski (C/RW) | Dallas Stars | 56 | 25 | 26 | 51 | 0.91 | 16 | 22 |
| 24. | Max Pacioretty (LW) | Vegas Golden Knights | 48 | 24 | 27 | 51 | 1.06 | 14 | 20 |
| 25. | Kyle Connor (LW) | Winnipeg Jets | 56 | 26 | 24 | 50 | 0.89 | 12 | -4 |
| 26. | Mika Zibanejad (C/RW) | New York Rangers | 56 | 24 | 26 | 50 | 0.89 | 18 | 2 |
| 27. | John Tavares (C/LW) | Toronto Maple Leafs | 56 | 19 | 31 | 50 | 0.89 | 14 | 12 |
| 28. | Anze Kopitar (C/LW) | Los Angeles Kings | 56 | 13 | 37 | 50 | 0.89 | 10 | -7 |
| 29. | Brock Boeser (RW/LW) | Vancouver Canucks | 56 | 23 | 26 | 49 | 0.88 | 16 | -3 |
| 30. | Evander Kane (LW/RW) | San Jose Sharks | 56 | 22 | 27 | 49 | 0.88 | 42 | -1 |
| 31. | Johnny Gaudreau (LW) | Calgary Flames | 56 | 19 | 30 | 49 | 0.88 | 6 | 2 |
| 32. | Ryan Strome (C/RW) | New York Rangers | 56 | 14 | 35 | 49 | 0.88 | 39 | 6 |
| 33. | Patrice Bergeron (C) | Boston Bruins | 54 | 23 | 25 | 48 | 0.89 | 16 | 27 |
| 34. | Brayden Point (C) | Tampa Bay Lightning | 56 | 23 | 25 | 48 | 0.86 | 11 | 2 |
| 35. | David Pastrnak (RW/LW) | Boston Bruins | 48 | 20 | 28 | 48 | 1.00 | 24 | 10 |
| 36. | Pavel Buchnevich (W/C) | New York Rangers | 54 | 20 | 28 | 48 | 0.89 | 42 | 12 |
| 37. | Tyson Barrie (D) | Edmonton Oilers | 56 | 8 | 40 | 48 | 0.86 | 10 | 4 |
| 38. | Elias Lindholm (C/RW) | Calgary Flames | 56 | 19 | 28 | 47 | 0.84 | 22 | 10 |
| 39. | Adam Fox (D) | New York Rangers | 55 | 5 | 42 | 47 | 0.85 | 14 | 19 |
| 40. | Nikolaj Ehlers (LW/RW) | Winnipeg Jets | 47 | 21 | 25 | 46 | 0.98 | 15 | 15 |
| 41. | Blake Wheeler (RW/C) | Winnipeg Jets | 50 | 15 | 31 | 46 | 0.92 | 50 | -17 |
| 42. | J.T. Miller (C/W) | Vancouver Canucks | 53 | 15 | 31 | 46 | 0.87 | 43 | -7 |
| 43. | Ondrej Palat (LW/RW) | Tampa Bay Lightning | 55 | 15 | 31 | 46 | 0.84 | 26 | 1 |
| 44. | Jason Robertson (LW/RW) | Dallas Stars | 51 | 17 | 28 | 45 | 0.88 | 16 | 13 |
| 45. | Mathew Barzal (C/RW) | New York Islanders | 55 | 17 | 28 | 45 | 0.82 | 48 | 15 |
| 46. | Victor Hedman (D) | Tampa Bay Lightning | 54 | 9 | 36 | 45 | 0.83 | 28 | 5 |
| 47. | Kris Letang (D) | Pittsburgh Penguins | 55 | 7 | 38 | 45 | 0.82 | 32 | 19 |
| 48. | Tyler Toffoli (RW/C) | Montréal Canadiens | 52 | 28 | 16 | 44 | 0.85 | 24 | 0 |
| 49. | André Burakovsky (LW/RW) | Colorado Avalanche | 53 | 19 | 25 | 44 | 0.83 | 10 | 4 |
| 50. | Jonathan Marchessault (LW/RW) | Vegas Golden Knights | 55 | 18 | 26 | 44 | 0.80 | 39 | 19 |
| 51. | Oliver Bjorkstrand (RW) | Columbus Blue Jackets | 56 | 18 | 26 | 44 | 0.79 | 23 | -15 |
| 52. | John Carlson (D) | Washington Capitals | 52 | 10 | 34 | 44 | 0.85 | 12 | -5 |
| 53. | Cale Makar (D) | Colorado Avalanche | 44 | 8 | 36 | 44 | 1.00 | 12 | 17 |
| 54. | David Krejčí (C) | Boston Bruins | 51 | 8 | 36 | 44 | 0.86 | 16 | 16 |
| 55. | T.J. Oshie (RW) | Washington Capitals | 53 | 22 | 21 | 43 | 0.81 | 18 | -3 |
| 56. | Phil Kessel (RW) | Arizona Coyotes | 56 | 20 | 23 | 43 | 0.77 | 12 | -17 |
| 57. | Tomas Hertl (C/LW) | San Jose Sharks | 50 | 19 | 24 | 43 | 0.86 | 27 | 1 |
| 58. | Vincent Trocheck (C) | Carolina Hurricanes | 47 | 17 | 26 | 43 | 0.91 | 20 | -3 |
| 59. | James van Riemsdyk (LW/RW) | Philadelphia Flyers | 56 | 17 | 26 | 43 | 0.77 | 14 | 2 |
| 60. | Claude Giroux (W/C) | Philadelphia Flyers | 54 | 16 | 27 | 43 | 0.80 | 12 | -4 |
| 61. | Matthew Tkachuk (LW/RW) | Calgary Flames | 56 | 16 | 27 | 43 | 0.77 | 55 | 6 |
| 62. | Roope Hintz (C/LW) | Dallas Stars | 41 | 15 | 28 | 43 | 1.05 | 4 | 13 |
| 63. | Jakub Voráček (RW) | Philadelphia Flyers | 53 | 9 | 34 | 43 | 0.81 | 18 | -12 |
| 64. | Alexander Ovechkin (LW/RW) | Washington Capitals | 45 | 24 | 18 | 42 | 0.93 | 12 | -7 |
| 65. | Bryan Rust (RW/LW) | Pittsburgh Penguins | 56 | 22 | 20 | 42 | 0.75 | 18 | 9 |
| 66. | William Nylander (W/C) | Toronto Maple Leafs | 51 | 17 | 25 | 42 | 0.82 | 16 | 10 |
| 67. | Andrei Svechnikov (RW/LW) | Carolina Hurricanes | 55 | 15 | 27 | 42 | 0.76 | 44 | 1 |
| 68. | Jeff Petry (D) | Montréal Canadiens | 55 | 12 | 30 | 42 | 0.76 | 20 | 6 |
| 69. | Dougie Hamilton (D) | Carolina Hurricanes | 55 | 10 | 32 | 42 | 0.76 | 35 | 20 |
| 70. | Shea Theodore (D) | Vegas Golden Knights | 53 | 8 | 34 | 42 | 0.79 | 14 | 28 |
| 71. | Sean Couturier (C) | Philadelphia Flyers | 45 | 18 | 23 | 41 | 0.91 | 8 | -4 |
| 72. | Jakob Chychrun (D) | Arizona Coyotes | 56 | 18 | 23 | 41 | 0.73 | 42 | -6 |
| 73. | Nick Suzuki (C) | Montréal Canadiens | 56 | 15 | 26 | 41 | 0.73 | 26 | -5 |
| 74. | Martin Nečas (C/RW) | Carolina Hurricanes | 53 | 14 | 27 | 41 | 0.77 | 10 | 25 |
| 75. | Quinn Hughes (D) | Vancouver Canucks | 56 | 3 | 38 | 41 | 0.73 | 22 | -24 |
| 76. | Sam Reinhart (C/RW) | Buffalo Sabres | 54 | 25 | 15 | 40 | 0.74 | 10 | -28 |
| 77. | Kevin Fiala (W/C) | Minnesota Wild | 50 | 20 | 20 | 40 | 0.80 | 43 | -2 |
| 78. | Bo Horvat (C) | Vancouver Canucks | 56 | 19 | 20 | 39 | 0.70 | 23 | -6 |
| 79. | Andrew Copp (C/LW) | Winnipeg Jets | 55 | 15 | 24 | 39 | 0.71 | 20 | 2 |
| 80. | William Karlsson (C) | Vegas Golden Knights | 56 | 14 | 25 | 39 | 0.70 | 4 | 19 |
| 81. | Conor Garland (RW/LW) | Arizona Coyotes | 49 | 12 | 27 | 39 | 0.80 | 26 | -3 |
| 82. | Joel Farabee (LW/RW) | Philadelphia Flyers | 55 | 20 | 18 | 38 | 0.69 | 28 | 0 |
| 83. | Dominik Kubalik (LW/RW) | Chicago Blackhawks | 56 | 17 | 21 | 38 | 0.68 | 18 | -3 |
| 84. | Jordan Staal (C/LW) | Carolina Hurricanes | 53 | 16 | 22 | 38 | 0.72 | 30 | 2 |
| 85. | Jakub Vrána (LW/RW) | totals | 50 | 19 | 17 | 36 | 0.72 | 10 | 10 |
| Washington Capitals | Washington Capitals | 39 | 11 | 14 | 25 | 0.64 | 8 | 9 |
| Detroit Red Wings | Detroit Red Wings | 11 | 8 | 3 | 11 | 1.00 | 2 | 1 |
| 86. | Carter Verhaeghe (C/LW) | Florida Panthers | 43 | 18 | 18 | 36 | 0.84 | 31 | 24 |
| 87. | Mike Hoffman (LW/C) | St. Louis Blues | 52 | 17 | 19 | 36 | 0.69 | 10 | 2 |
| 88. | Yanni Gourde (C/W) | Tampa Bay Lightning | 56 | 17 | 19 | 36 | 0.64 | 44 | 10 |
| 89. | Brady Tkachuk (LW) | Ottawa Senators | 56 | 17 | 19 | 36 | 0.64 | 69 | -17 |
| 90. | Brayden Schenn (C/W) | St. Louis Blues | 56 | 16 | 20 | 36 | 0.64 | 35 | -2 |
| 91. | Darnell Nurse (D) | Edmonton Oilers | 56 | 16 | 20 | 36 | 0.64 | 57 | 27 |
| 92. | John Klingberg (D) | Dallas Stars | 53 | 7 | 29 | 36 | 0.68 | 23 | -15 |
| 93. | MacKenzie Weegar (D) | Florida Panthers | 54 | 6 | 30 | 36 | 0.67 | 45 | 29 |
| 94. | Connor Brown (RW/LW) | Ottawa Senators | 56 | 21 | 14 | 35 | 0.63 | 12 | 1 |
| 95. | Pavel Zacha (C/LW) | New Jersey Devils | 50 | 17 | 18 | 35 | 0.70 | 10 | -11 |
| 96. | Josh Norris (C/LW) | Ottawa Senators | 56 | 17 | 18 | 35 | 0.63 | 13 | -12 |
| 97. | Ryan Nugent-Hopkins (C/W) | Edmonton Oilers | 52 | 16 | 19 | 35 | 0.67 | 22 | -4 |
| 98. | Chandler Stephenson (C/LW) | Vegas Golden Knights | 51 | 14 | 21 | 35 | 0.69 | 29 | 22 |
| 99. | Jordan Kyrou (C/RW) | St. Louis Blues | 55 | 14 | 21 | 35 | 0.64 | 12 | 1 |
| 100. | Clayton Keller (RW/LW) | Arizona Coyotes | 56 | 14 | 21 | 35 | 0.63 | 18 | -5 |