| 1. |  Jack Eichel (C) | | totals | 65 | 26 | 54 | 80 | 14 |
| | Vegas Golden Knights | NHL | 59 | 24 | 50 | 74 | 12 |
| | USA Olympics | OG | 6 | 2 | 4 | 6 | 2 |
| 2. | Matt Boldy (LW/RW) | | totals | 70 | 40 | 39 | 79 | 30 |
| | Minnesota Wild | NHL | 64 | 38 | 37 | 75 | 28 |
| | USA Olympics | OG | 6 | 2 | 2 | 4 | 2 |
| 3. | Jason Robertson (LW/RW) | Dallas Stars | NHL | 66 | 36 | 43 | 79 | 24 |
| 4. | Kyle Connor (LW) | | totals | 68 | 31 | 44 | 75 | 16 |
| |  Winnipeg Jets | NHL | 66 | 31 | 44 | 75 | 16 |
| | USA Olympics | OG | 2 | 0 | 0 | 0 | 0 |
| 5. | Quinn Hughes (D) | | totals | 68 | 7 | 68 | 75 | 28 |
| | Vancouver Canucks | NHL | 26 | 2 | 21 | 23 | 12 |
| | USA Olympics | OG | 6 | 1 | 7 | 8 | 0 |
| | Minnesota Wild | NHL | 36 | 4 | 40 | 44 | 16 |
| 6. | Tage Thompson (C/W) | | totals | 73 | 37 | 37 | 74 | 29 |
| | Buffalo Sabres | NHL | 67 | 34 | 36 | 70 | 29 |
| | USA Olympics | OG | 6 | 3 | 1 | 4 | 0 |
| 7. | Zach Werenski (D) | | totals | 65 | 21 | 53 | 74 | 16 |
| | Columbus Blue Jackets | NHL | 59 | 20 | 48 | 68 | 12 |
| | USA Olympics | OG | 6 | 1 | 5 | 6 | 4 |
| 8. | Lane Hutson (D) | Montréal Canadiens | NHL | 66 | 11 | 56 | 67 | 30 |
| 9. | Cole Caufield (LW/RW) | Montréal Canadiens | NHL | 65 | 39 | 27 | 66 | 14 |
| 10. | Alex DeBrincat (RW/LW) | Detroit Red Wings | NHL | 67 | 33 | 33 | 66 | 12 |
| 11. | Clayton Keller (RW/LW) | | totals | 71 | 19 | 45 | 64 | 26 |
| | Utah Mammoth | NHL | 67 | 19 | 45 | 64 | 26 |
| | USA Olympics | OG | 4 | 0 | 0 | 0 | 0 |
| 12. | Riley Barber (RW/LW) |  ERC Ingolstadt | DEL | 52 | 32 | 31 | 63 | 29 |
| 13. | Auston Matthews (C/LW) | | totals | 66 | 30 | 30 | 60 | 22 |
| | Toronto Maple Leafs | NHL | 60 | 27 | 26 | 53 | 18 |
| | USA Olympics | OG | 6 | 3 | 4 | 7 | 4 |
| 14. | Cutter Gauthier (LW/C) | Anaheim Ducks | NHL | 66 | 34 | 25 | 59 | 24 |
| 15. | Nick Schmaltz (C/RW) | Utah Mammoth | NHL | 67 | 24 | 35 | 59 | 26 |
| 16. | Brock Nelson (C/LW) | | totals | 71 | 32 | 26 | 58 | 26 |
| | Colorado Avalanche | NHL | 65 | 30 | 25 | 55 | 26 |
| | USA Olympics | OG | 6 | 2 | 1 | 3 | 0 |
| 17. | Dylan Larkin (C/LW) | | totals | 69 | 30 | 28 | 58 | 46 |
| | Detroit Red Wings | NHL | 63 | 28 | 27 | 55 | 42 |
| | USA Olympics | OG | 6 | 2 | 1 | 3 | 4 |
| 18. | Alex Tuch (RW/C) | Buffalo Sabres | NHL | 65 | 28 | 29 | 57 | 49 |
| 19. | Jack Hughes (C/LW) | | totals | 51 | 21 | 34 | 55 | 6 |
| | New Jersey Devils | NHL | 45 | 17 | 31 | 48 | 4 |
| | USA Olympics | OG | 6 | 4 | 3 | 7 | 2 |
| 20. | Trevor Zegras (C/W) | Philadelphia Flyers | NHL | 66 | 22 | 32 | 54 | 42 |
| 21. | Brady Tkachuk (LW) | | totals | 52 | 21 | 30 | 51 | 60 |
| | Ottawa Senators | NHL | 46 | 18 | 28 | 46 | 48 |
| | USA Olympics | OG | 6 | 3 | 2 | 5 | 12 |
| 22. | Charlie Coyle (C/RW) | Columbus Blue Jackets | NHL | 66 | 16 | 35 | 51 | 10 |
| 23. | Jake Sanderson (D) | | totals | 68 | 11 | 39 | 50 | 8 |
| | Ottawa Senators | NHL | 62 | 11 | 37 | 48 | 8 |
| | USA Olympics | OG | 6 | 0 | 2 | 2 | 0 |
| 24. | Zac Jones (D) | Rochester Americans | AHL | 47 | 8 | 42 | 50 | 12 |
| 25. | Patrick Brown (C/RW) | Providence Bruins | AHL | 58 | 17 | 32 | 49 | 46 |
| 26. | Vincent Trocheck (C) | | totals | 57 | 13 | 36 | 49 | 50 |
| | New York Rangers | NHL | 51 | 13 | 33 | 46 | 48 |
| | USA Olympics | OG | 6 | 0 | 3 | 3 | 2 |
| 27. | Charlie McAvoy (D) | | totals | 60 | 9 | 40 | 49 | 56 |
| | Boston Bruins | NHL | 54 | 9 | 40 | 49 | 50 |
| | USA Olympics | OG | 6 | 0 | 0 | 0 | 6 |
| 28. | Jackson LaCombe (D) | | totals | 67 | 8 | 39 | 47 | 17 |
| | Anaheim Ducks | NHL | 67 | 8 | 39 | 47 | 17 |
| | USA Olympics | OG | 0 | 0 | 0 | 0 | 0 |
| 29. | Will Smith (C/RW) | San Jose Sharks | NHL | 52 | 19 | 26 | 45 | 14 |
| 30. | Josh Doan (W/C) | Buffalo Sabres | NHL | 67 | 21 | 23 | 44 | 23 |
| 31. | Ryan Lasch (RW) |  Vålerenga | Norway | 39 | 14 | 30 | 44 | 12 |
| 32. | Alexander Chmelevski (C) | | totals | 64 | 18 | 25 | 43 | 18 |
| |  Salavat Yulaev Ufa | KHL | 6 | 1 | 2 | 3 | 2 |
| | Ak Bars Kazan | KHL | 58 | 17 | 23 | 40 | 16 |
| 33. | Matty Beniers (C) | Seattle Kraken | NHL | 66 | 18 | 25 | 43 | 23 |
| 34. | Chris Kreider (LW/RW) | Anaheim Ducks | NHL | 61 | 21 | 21 | 42 | 26 |
| 35. | Isaac Howard (LW/RW) | | totals | 63 | 18 | 22 | 40 | 20 |
| | Edmonton Oilers | NHL | 28 | 2 | 3 | 5 | 12 |
| | Bakersfield Condors | AHL | 35 | 16 | 19 | 35 | 8 |
| 36. | Sean Farrell (C/LW) | Laval Rocket | AHL | 61 | 13 | 27 | 40 | 18 |
| 37. | T.J. Tynan (C/RW) | | totals | 55 | 3 | 37 | 40 | 38 |
| | Colorado Eagles | AHL | 54 | 3 | 37 | 40 | 38 |
| | Colorado Avalanche | NHL | 1 | 0 | 0 | 0 | 0 |
| 38. | Christian Dvorak (C/LW) | Philadelphia Flyers | NHL | 65 | 13 | 26 | 39 | 18 |
| 39. | Vinni Lettieri (C/RW) | Toronto Marlies | AHL | 47 | 12 | 27 | 39 | 30 |
| 40. | Patrick Kane (RW/LW) | Detroit Red Wings | NHL | 52 | 10 | 28 | 38 | 14 |
| 41. | Scott Perunovich (D) | Tucson Roadrunners | AHL | 54 | 7 | 31 | 38 | 46 |
| 42. | Andrew Copp (C/LW) | Detroit Red Wings | NHL | 65 | 8 | 29 | 37 | 22 |
| 43. | Shane Pinto (C) | Ottawa Senators | NHL | 56 | 17 | 19 | 36 | 38 |
| 44. | Rocco Grimaldi (LW/C) | SKA St. Petersburg | KHL | 64 | 15 | 20 | 35 | 26 |
| 45. | Anders Lee (LW) | New York Islanders | NHL | 67 | 15 | 20 | 35 | 29 |
| 46. | Jimmy Vesey (LW/RW) |  Genève-Servette HC | NL | 52 | 14 | 21 | 35 | 16 |
| 47. | Ryan Leonard (C) | Washington Capitals | NHL | 61 | 14 | 21 | 35 | 34 |
| 48. | Justin Faulk (D) | | totals | 65 | 12 | 22 | 34 | 34 |
| | St. Louis Blues | NHL | 61 | 11 | 21 | 32 | 32 |
| | Detroit Red Wings | NHL | 4 | 1 | 1 | 2 | 2 |
| 49. | Jordan Oesterle (D) | Milwaukee Admirals | AHL | 56 | 7 | 27 | 34 | 24 |
| 50. | Adam Fox (D) | New York Rangers | NHL | 39 | 5 | 29 | 34 | 16 |
| 51. | Kevin Labanc (RW/LW) |  Shanghai Dragons | KHL | 53 | 14 | 19 | 33 | 58 |
| 52. | Colin White (C/RW) | San Jose Barracuda | AHL | 34 | 12 | 21 | 33 | 24 |
| 53. | Frank Nazar (C/RW) | Chicago Blackhawks | NHL | 50 | 10 | 22 | 32 | 24 |
| 54. | Jacob Trouba (D) | Anaheim Ducks | NHL | 66 | 10 | 22 | 32 | 29 |
| 55. | Luke Hughes (D) | New Jersey Devils | NHL | 56 | 6 | 26 | 32 | 28 |
| 56. | Daniel Brickley (D) |  Tappara | Liiga | 50 | 6 | 25 | 31 | 14 |
| 57. | Kieffer Bellows (LW/RW) |  Brynäs IF | SHL | 52 | 15 | 15 | 30 | 33 |
| 58. | Ryan Hartman (RW/C) | Minnesota Wild | NHL | 64 | 15 | 15 | 30 | 36 |
| 59. | Joel Farabee (LW/RW) | Calgary Flames | NHL | 66 | 15 | 15 | 30 | 22 |
| 60. | Matt Coronato (RW/LW) | Calgary Flames | NHL | 65 | 14 | 16 | 30 | 18 |
| 61. | Alexander Galchenyuk (C/RW) | Amur Khabarovsk | KHL | 50 | 13 | 17 | 30 | 12 |
| 62. | Conor Garland (RW/LW) | | totals | 55 | 11 | 19 | 30 | 30 |
| | Vancouver Canucks | NHL | 50 | 7 | 19 | 26 | 30 |
| | Columbus Blue Jackets | NHL | 5 | 4 | 0 | 4 | 0 |
| 63. | Adam Clendening (D) | Shanghai Dragons | KHL | 64 | 3 | 27 | 30 | 68 |
| 64. | Logan Cooley (C/LW) | Utah Mammoth | NHL | 39 | 17 | 12 | 29 | 24 |
| 65. | Andy Miele (C) | Fischtown Pinguins | DEL | 51 | 7 | 22 | 29 | 53 |
| 66. | Ben Meyers (C/LW) | | totals | 52 | 16 | 12 | 28 | 11 |
| | Coachella Valley Firebirds | AHL | 11 | 9 | 4 | 13 | 2 |
| | Seattle Kraken | NHL | 41 | 7 | 8 | 15 | 9 |
| 67. | James van Riemsdyk (LW/RW) | Detroit Red Wings | NHL | 58 | 15 | 13 | 28 | 12 |
| 68. | Ryan Donato (C/W) | Chicago Blackhawks | NHL | 66 | 14 | 13 | 27 | 36 |
| 69. | Ryan Shea (D) | Pittsburgh Penguins | NHL | 66 | 4 | 23 | 27 | 22 |
| 70. | Blake Coleman (LW/RW) | Calgary Flames | NHL | 54 | 16 | 10 | 26 | 35 |
| 71. | Noah Hanifin (D) | | totals | 62 | 4 | 22 | 26 | 8 |
| | Vegas Golden Knights | NHL | 56 | 3 | 20 | 23 | 8 |
| | USA Olympics | OG | 6 | 1 | 2 | 3 | 0 |
| 72. | Drew O'Connor (LW/RW) | Vancouver Canucks | NHL | 66 | 15 | 10 | 25 | 34 |
| 73. | Karson Kuhlman (C/RW) | Rögle BK | SHL | 52 | 13 | 12 | 25 | 8 |
| 74. | Cam Fowler (D) | St. Louis Blues | NHL | 67 | 2 | 23 | 25 | 14 |
| 75. | Christian Wolanin (D) | Providence Bruins | AHL | 43 | 7 | 17 | 24 | 10 |
| 76. | Mason Lohrei (D) | Boston Bruins | NHL | 61 | 7 | 17 | 24 | 16 |
| 77. | Seth Jones (D) | Florida Panthers | NHL | 40 | 6 | 18 | 24 | 16 |
| 78. | Kevin Rooney (C/LW) | | totals | 39 | 13 | 10 | 23 | 6 |
| | Tucson Roadrunners | AHL | 38 | 12 | 10 | 22 | 6 |
| | Utah Mammoth | NHL | 1 | 1 | 0 | 1 | 0 |
| 79. | Sammy Walker (C/RW) | Tucson Roadrunners | AHL | 44 | 9 | 13 | 22 | 12 |
| 80. | Zeev Buium (D) | | totals | 60 | 5 | 17 | 22 | 18 |
| | Minnesota Wild | NHL | 31 | 3 | 11 | 14 | 8 |
| | Vancouver Canucks | NHL | 29 | 2 | 6 | 8 | 10 |
| 81. | Adam Gaudette (W/C) | San Jose Sharks | NHL | 52 | 14 | 7 | 21 | 16 |
| 82. | Austin Watson (LW/RW) | Grand Rapids Griffins | AHL | 50 | 11 | 10 | 21 | 144 |
| 83. | J.T. Compher (W/C) | Detroit Red Wings | NHL | 67 | 9 | 12 | 21 | 25 |
| 84. | Jack Drury (C/LW) | Colorado Avalanche | NHL | 65 | 8 | 13 | 21 | 20 |
| 85. | Nick Blankenburg (D) | | totals | 51 | 6 | 15 | 21 | 10 |
| | Nashville Predators | NHL | 49 | 6 | 15 | 21 | 10 |
| | Colorado Avalanche | NHL | 2 | 0 | 0 | 0 | 0 |
| 86. | John Hayden (C/RW) | | totals | 55 | 11 | 9 | 20 | 117 |
| | Coachella Valley Firebirds | AHL | 52 | 11 | 9 | 20 | 115 |
| | Seattle Kraken | NHL | 3 | 0 | 0 | 0 | 2 |
| 87. | Henry Thrun (D) | | totals | 46 | 4 | 16 | 20 | 19 |
| | Toronto Marlies | AHL | 42 | 4 | 16 | 20 | 19 |
| | Toronto Maple Leafs | NHL | 4 | 0 | 0 | 0 | 0 |
| 88. | Jake McCabe (D) | Toronto Maple Leafs | NHL | 66 | 3 | 17 | 20 | 44 |
| 89. | Trevor Moore (W/C) | Los Angeles Kings | NHL | 53 | 8 | 11 | 19 | 8 |
| 90. | Will Butcher (D) | Cleveland Monsters | AHL | 49 | 3 | 16 | 19 | 8 |
| 91. | Brady Skjei (D) | Nashville Predators | NHL | 66 | 1 | 18 | 19 | 26 |
| 92. | Michael Eyssimont (C/LW) | Boston Bruins | NHL | 51 | 8 | 10 | 18 | 31 |
| 93. | Sonny Milano (LW) | | totals | 39 | 7 | 11 | 18 | 4 |
| | Washington Capitals | NHL | 31 | 4 | 4 | 8 | 4 |
| | Hershey Bears | AHL | 8 | 3 | 7 | 10 | 0 |
| 94. | Kyle Palmieri (RW) | New York Islanders | NHL | 25 | 6 | 12 | 18 | 8 |
| 95. | Nate Schmidt (D) | Utah Mammoth | NHL | 67 | 4 | 14 | 18 | 18 |
| 96. | Nick Jensen (D) | Ottawa Senators | NHL | 61 | 4 | 13 | 17 | 22 |
| 97. | Alex Vlasic (D) | Chicago Blackhawks | NHL | 65 | 2 | 15 | 17 | 13 |
| 98. | Eric Robinson (LW/RW) | Carolina Hurricanes | NHL | 53 | 11 | 5 | 16 | 4 |
| 99. | Thomas Bordeleau (C/LW) | | totals | 49 | 7 | 9 | 16 | 41 |
| | Utica Comets | AHL | 35 | 2 | 6 | 8 | 37 |
| | Springfield Thunderbirds | AHL | 14 | 5 | 3 | 8 | 4 |
| 100. | Steve Moses (RW) | | totals | 39 | 6 | 10 | 16 | 10 |
| |  BK Mladá Boleslav | Czechia | 28 | 1 | 9 | 10 | 4 |
| | Mountfield HK | Czechia | 11 | 5 | 1 | 6 | 6 |
